Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GPX4 | P36969 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8345485 | 0.86 | KCNH2 (0.47) | FFAR1MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL7362325 | 0.80 | FFAR1 (0.42) | FFAR1FFAR4MAOBMEN1KMT2A | |
| SCHEMBL7357492 | 0.80 | FFAR1 (0.47) | FFAR1FFAR4MAOBMEN1KMT2A | |
| SCHEMBL7368439 | 0.77 | PDCD1 (0.40) | FFAR1FFAR4KCNN4KCNA5PPARG | |
| SCHEMBL7368444 | 0.75 | FFAR1 (0.41) | FFAR1FFAR4MAOBMEN1KMT2A | |
| SCHEMBL7362467 | 0.73 | FFAR1 (0.53) | FFAR1FFAR4MEN1KMT2AUSP2 | |
| SCHEMBL14229160 | 0.71 | TP53 (0.52) | FFAR1MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL7464051 | 0.70 | PDCD1 (0.42) | FFAR1FFAR4MAOBKCNN4KCNA5 | |
| SCHEMBL7459672 | 0.70 | FFAR1 (0.41) | FFAR1FFAR4MEN1KMT2AUSP2 | |
| SCHEMBL10019242 | 0.69 | KCNN4 (0.41) | FFAR1ALDH1A1RAB9AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942544-A | α-branched anilines, toluenes, and analogs thereof as factor Xa inhibitors | DUPONT PHARMACEUTICALS COMPANY (US) | 1999-08-24 | — | — | US | disclosed |