Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1A1 | P14550 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 3/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25370049 | 0.88 | AKR1A1 (0.45) | AKR1A1AKR1B1SMN1; SMN2PTGDR2KMT2A | |
| SCHEMBL25084322 | 0.84 | IDO1 (0.52) | AKR1A1AKR1B1SMN1; SMN2GAAIDO1 | |
| SCHEMBL18549620 | 0.81 | IDO1 (0.49) | AKR1A1AKR1B1SMN1; SMN2GAAIDO1 | |
| SCHEMBL26901577 | 0.81 | SMN1; SMN2 (0.44) | AKR1A1AKR1B1SMN1; SMN2GAAIDO1 | |
| SCHEMBL17023688 | 0.81 | CFD (0.49) | AKR1A1AKR1B1SMN1; SMN2GAAIDO1 | |
| SCHEMBL29781757 | 0.81 | CFD (0.49) | AKR1A1AKR1B1SMN1; SMN2GAAIDO1 | |
| SCHEMBL23368384 | 0.79 | SMN1; SMN2 (0.48) | AKR1A1AKR1B1SMN1; SMN2GAAIDO1 | |
| SCHEMBL443715 | 0.77 | KRAS (0.59) | AKR1A1AKR1B1SMN1; SMN2GAAIDO1 | |
| SCHEMBL2546174 | 0.77 | KMT2A (0.62) | GAAPTGDR2KMT2ASTAT3TBXAS1 | |
| SCHEMBL28598442 | 0.76 | PTGDR2 (0.41) | PTGDR2KMT2ASTAT3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1231916-A2 | USE OF INDIRUBINE DERIVATIVES FOR MAKING MEDICINES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001037819-A2 | USE OF INDIRUBINE DERIVATIVES FOR MAKING MEDICINES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2001-05-31 | — | — | WO | disclosed |
| US-5789652-A | BIOCHEMICAL GENE MARKERS IN ORGANS, BLOOD WITH ERYTHROCYTES,LYMPHOCYTES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-08-04 | — | — | US | disclosed |