Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7362367 | 1.00 | IDO1 (0.41) | IDO1MAPTRAB9ANPC1L3MBTL1 | |
| SCHEMBL25277063 | 0.81 | MAPT (0.51) | IDO1MAPTRAB9ANPC1L3MBTL1 | |
| SCHEMBL4906930 | 0.79 | TDP1 (0.59) | IDO1MAPTL3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL4906925 | 0.79 | TDP1 (0.59) | IDO1MAPTL3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL28417525 | 0.74 | MAPT (0.51) | IDO1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28458346 | 0.71 | CYP2A6 (0.49) | IDO1MAPTL3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL18448000 | 0.71 | IDO1 (0.48) | IDO1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28143021 | 0.70 | ALDH1A1 (0.60) | SMN1; SMN2TDP1LMNACA12CA1 | |
| SCHEMBL18448503 | 0.70 | MAPT (0.49) | IDO1MAPTRAB9ANPC1PKM | |
| SCHEMBL9430137 | 0.69 | MAPT (0.45) | IDO1MAPTRAB9ANPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1068187-A1 | PYRAZOLE INHIBITORS OF CYTOKINE PRODUCTION | ABBOTT LABORATORIES (US) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999051580-A1 | PYRAZOLE INHIBITORS OF CYTOKINE PRODUCTION | ABBOTT LABORATORIES (US) | 1999-10-14 | — | — | WO | disclosed |