Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 7/20 | 1.00 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.52 |
| ▸ | HTR3B | O95264 | 2/20 | 0.52 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.52 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7363031 | 0.99 | HTR3A (0.98) | HTR3ACHRNA7TSHRALDH1A1CYP1A2 | |
| SCHEMBL7360573 | 0.87 | HTR3A (0.77) | HTR3ACHRNA7TSHRALDH1A1CYP1A2 | |
| SCHEMBL7362191 | 0.81 | HTR3A (0.67) | HTR3ACHRNA7 | |
| SCHEMBL1761694 | 0.77 | HTR3A (0.62) | HTR3AALDH1A1 | |
| SCHEMBL6415345 | 0.76 | HTR3A (0.61) | HTR3ACHRNA7TSHRALDH1A1CYP1A2 | |
| SCHEMBL6418471 | 0.76 | HTR3A (0.61) | HTR3ACHRNA7TSHRALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL6415456 | 0.75 | HTR3A (0.60) | HTR3ACHRNA7TSHRALDH1A1CYP1A2 | |
| SCHEMBL6419010 | 0.74 | CHRNA7 (0.83) | HTR3ACHRNA7TSHRHTR3EHTR3B | |
| SCHEMBL9646418 | 0.74 | HTR3A (0.66) | HTR3ACHRNA7TSHRKCNH2HTR3E | |
| SCHEMBL7386037 | 0.74 | HTR3A (0.59) | HTR3ACYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530353-A1 | NEW IMIDAZOPYRIDINES AS SEROTONERGIC 5-HT 3? ANTAGONISTS | G.D. SEARLE & CO. (US) | 1993-03-10 | — | — | EP | claimed |
| WO-1992015593-A1 | NEW IMIDAZOPYRIDINES AS SEROTONERGIC 5-HT3 ANTAGONISTS | G.D. SEARLE & CO. (US) | 1992-09-17 | — | — | WO | claimed |
| WO-2004094418-A1 | IMIDAZOPYRIDINE COMPOUNDS HAVING 5-HT4 RECEPTOR AGONISTIC ACTIVITY AND 5-HT3 RECEPTOR ANTAGONISTIC ACTIVITY | PFIZER INC. (US) | 2004-11-04 | — | — | WO | disclosed |