SCHEMBL736279

SCHEMBL736279

C=CC(=O)NC(CC)C(C)(C)CS(=O)(=O)O

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.43
ACACB O00763 2/20 0.34
ZDHHC20 Q5W0Z9 1/20 0.33
ZDHHC2 Q9UIJ5 1/20 0.33
ALDH1A1 P00352 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28901879 0.81 TSHR (0.46) TSHRACACBZDHHC20ZDHHC2ALDH1A1
SCHEMBL10793416 0.78 TSHR (0.41) TSHRACACBZDHHC20ZDHHC2ALDH1A1
SCHEMBL29192563 0.77 TSHR (0.39) TSHRZDHHC20ZDHHC2ALDH1A1CYP3A4
SCHEMBL15397868 0.75 TSHR (0.56) TSHRZDHHC20ZDHHC2ALDH1A1CYP3A4
SCHEMBL29192600 0.75 TSHR (0.41) TSHRZDHHC20ZDHHC2ALDH1A1CYP3A4
SCHEMBL28887767 0.74 TSHR (0.38) TSHRZDHHC20ZDHHC2
Sulfuric Acid SCHEMBL6253912 0.73 TSHR (0.52) TSHRACACBZDHHC20ZDHHC2ALDH1A1
SCHEMBL7625494 0.73 ALDH1A1 (0.40) TSHRZDHHC20ZDHHC2ALDH1A1CYP3A4
SCHEMBL19490 0.73 ALDH1A1 (0.47) TSHRZDHHC20ZDHHC2ALDH1A1CYP3A4
SCHEMBL28723020 0.73 ALDH1A1 (0.47) TSHRZDHHC20ZDHHC2ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8138289-B2 A matrix of a crosslinked polyampholyte having a cavity capable of selectively binding to a template of microorganisms, bacteria, proteins, nucleic acids; cartridges for blood dialysis (HIV); purification by washing a chromatography column loaded with a cell/tissue extracted virus followed by elution UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2012-03-20 US claimed
EP-2134757-A2 IMPRINTED POLYMERIC MATERIALS FOR BINDING VARIOUS TARGETS SUCH AS VIRUSES University of Maryland, College Park (US) 2009-12-23 EP claimed
US-20080241185-A1 IMPRINTED POLYMERIC MATERIALS FOR BINDING VARIOUS TARGETS SUCH AS VIRUSES UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2008-10-02 US claimed
WO-2008118662-A2 IMPRINTED POLYMERIC MATERIALS FOR BINDING VARIOUS TARGETS SUCH AS VIRUSES UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2008-10-02 WO claimed
WO-2025103901-A1 POLYMER DISPERSIONS FOR COATINGS BASF SE (DE) 2025-05-22 WO disclosed
EP-4136130-A1 AQUEOUS POLYMER DISPERSIONS BASF SE (DE) 2023-02-22 EP disclosed
WO-2021209543-A1 AQUEOUS POLYMER DISPERSIONS BASF SE (DE) 2021-10-21 WO disclosed
US-8138289-B2 A matrix of a crosslinked polyampholyte having a cavity capable of selectively binding to a template of microorganisms, bacteria, proteins, nucleic acids; cartridges for blood dialysis (HIV); purification by washing a chromatography column loaded with a cell/tissue extracted virus followed by elution UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2012-03-20 US disclosed
EP-2134757-A2 IMPRINTED POLYMERIC MATERIALS FOR BINDING VARIOUS TARGETS SUCH AS VIRUSES University of Maryland, College Park (US) 2009-12-23 EP disclosed
WO-2008118662-A2 IMPRINTED POLYMERIC MATERIALS FOR BINDING VARIOUS TARGETS SUCH AS VIRUSES UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2008-10-02 WO disclosed
US-20080241185-A1 IMPRINTED POLYMERIC MATERIALS FOR BINDING VARIOUS TARGETS SUCH AS VIRUSES UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2008-10-02 US disclosed