SCHEMBL29192563

SCHEMBL29192563

C=CC(=O)NC(C)(CS(=O)(=O)O)C(C)CC

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39
ALDH1A1 P00352 3/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
ZDHHC20 Q5W0Z9 1/20 0.37
ZDHHC2 Q9UIJ5 1/20 0.37
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
MAPK1 P28482 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TGM2 P21980 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29192600 0.87 TSHR (0.41) TSHRALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL8576089 0.83 TSHR (0.37) TSHRALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL9798795 0.81 ALDH1A1 (0.40) TSHRALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL28723020 0.81 ALDH1A1 (0.47) TSHRALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL19490 0.81 ALDH1A1 (0.47) TSHRALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL7625494 0.81 ALDH1A1 (0.40) TSHRALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL137801 0.81 TSHR (0.45) TSHRALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL363117 0.81 ALDH1A1 (0.37) TSHRALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL1618431 0.80 ALDH1A1 (0.39) TSHRALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL121582 0.80 ALDH1A1 (0.46) TSHRALDH1A1CYP3A4CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117585963-A Shrinkage-reducing anti-cracking type large-volume concrete and preparation method thereof 中建商品混凝土有限公司 2024-02-23 CN claimed
CN-117585963-A Shrinkage-reducing anti-cracking type large-volume concrete and preparation method thereof 中建商品混凝土有限公司 2024-02-23 CN disclosed