Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 9/20 | 0.72 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7362875 | 1.00 | SERPINE1 (0.72) | SERPINE1KAT2BTNKSHTR7HTR1A | |
| SCHEMBL7355821 | 0.88 | SERPINE1 (0.64) | SERPINE1 | |
| SCHEMBL7355836 | 0.88 | SERPINE1 (0.64) | SERPINE1 | |
| SCHEMBL8806544 | 0.85 | SERPINE1 (0.68) | SERPINE1KAT2B | |
| SCHEMBL7360011 | 0.85 | SERPINE1 (0.77) | SERPINE1 | |
| SCHEMBL7360006 | 0.85 | SERPINE1 (0.77) | SERPINE1 | |
| SCHEMBL7359303 | 0.84 | SERPINE1 (1.00) | SERPINE1KAT2BHTR7HTR1AHTR2A | |
| SCHEMBL7359291 | 0.84 | SERPINE1 (1.00) | SERPINE1KAT2BHTR7HTR1AHTR2A | |
| SCHEMBL7359356 | 0.82 | SERPINE1 (0.70) | SERPINE1HTR7HTR1AHTR2A | |
| SCHEMBL7359365 | 0.82 | SERPINE1 (0.70) | SERPINE1HTR7HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995032190-A2 | PHARMACEUTICAL DIKETOPIPERAZINE COMPOUNDS | XENOVA LIMITED (GB) | 1995-11-30 | — | — | WO | claimed |
| US-5750530-A | PLASMINOGEN ACTIVATOR INHIBITORS | XENOVA LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |
| EP-0760812-A1 | PHARMACEUTICAL DIKETOPIPERAZINE COMPOUNDS | XENOVA LIMITED (GB) | 1997-03-12 | — | — | EP | disclosed |
| WO-1995032190-A2 | PHARMACEUTICAL DIKETOPIPERAZINE COMPOUNDS | XENOVA LIMITED (GB) | 1995-11-30 | — | — | WO | disclosed |