Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7141327 | 0.86 | MAOA (0.56) | MAOAMAOBBCHEADRA2BADRA2C | |
| SCHEMBL11010091 | 0.83 | MAOA (0.52) | MAOAMAOBBCHEADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL9725935 | 0.82 | MAOA (0.51) | MAOAMAOBBCHEADRA2BADRA2C | |
| SCHEMBL3375618 | 0.80 | PDE4A (0.52) | MEN1ALDH1A1HTTKMT2APDPK1 | |
| SCHEMBL30047267 | 0.80 | PDE4A (0.52) | MEN1ALDH1A1HTTKMT2APDPK1 | |
| SCHEMBL30468602 | 0.80 | PDE4A (0.52) | MEN1ALDH1A1HTTKMT2APDPK1 | |
| SCHEMBL3375614 | 0.80 | PDE4A (0.52) | MEN1ALDH1A1HTTKMT2APDPK1 | |
| SCHEMBL2467861 | 0.79 | MAOA (0.56) | MAOAMAOBBCHEADRA2BADRA2C | |
| SCHEMBL92713 | 0.79 | MAOA (0.56) | MAOAMAOBBCHEADRA2BADRA2C | |
| SCHEMBL3932599 | 0.79 | MAOA (0.56) | MAOAMAOBBCHEADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115409-A2 | Indane derivatives, their production and use thereof | Takeda Chemical Industries, Ltd. (JP) | 1984-08-08 | — | — | EP | disclosed |