Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9725935 | 0.99 | MAOA (0.51) | MAOAMAOBBCHEADRA2BADRA2C | |
| SCHEMBL11005532 | 0.92 | ALDH1A1 (0.58) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| Hydrochloric Acid SCHEMBL11012783 | 0.91 | ALDH1A1 (0.57) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| SCHEMBL7141327 | 0.87 | MAOA (0.56) | MAOAMAOBBCHEADRA2BADRA2C | |
| SCHEMBL7419274 | 0.87 | ALDH1A1 (0.52) | MAOAMAOBBCHEADRA2BADRA2C | |
| SCHEMBL19969355 | 0.83 | NAMPT (0.54) | MAOAMAOBBCHEADRA2BADRA2C | |
| SCHEMBL23226905 | 0.83 | ALDH1A1 (0.59) | ALDH1A1KMT2AMEN1LMNANTRK1 | |
| SCHEMBL7362950 | 0.83 | MAOA (0.51) | MAOAMAOBBCHEADRA2BADRA2C | |
| SCHEMBL26291406 | 0.82 | ALDH1A1 (0.43) | ACHEALDH1A1KMT2AHPGDCA1 | |
| SCHEMBL11005443 | 0.81 | MAOA (0.49) | MAOAMAOBBCHEACHEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4521607-A | HYPOTENSIVE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-06-04 | — | — | US | disclosed |
| EP-0051391-B1 | BICYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1984-09-05 | — | — | EP | disclosed |
| EP-0035868-A1 | Bicyclic compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1981-09-16 | — | — | EP | disclosed |