Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM2 | P50570 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CDC7 | O00311 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.46 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30329781 | 0.98 | DNM2 (0.51) | DNM2PDE4APTGS2KDM4EATM | |
| SCHEMBL935515 | 0.88 | PDE4A (0.56) | PDE4AKDM4ERAB9ASMN1; SMN2CDC7 | |
| SCHEMBL9085610 | 0.86 | PDE4A (0.53) | PDE4AKDM4ERAB9ACDC7CHEK1 | |
| SCHEMBL7357755 | 0.85 | MCHR1 (0.43) | DNM2PDE4APTGS2KDM4EATM | |
| SCHEMBL7363295 | 0.83 | DNM2 (0.42) | DNM2PDE4APTGS2KDM4EATM | |
| SCHEMBL19686921 | 0.81 | IDH1 (0.53) | — | |
| SCHEMBL4000110 | 0.81 | PDE4A (0.58) | DNM2PDE4AKDM4ERAB9ALMNA | |
| SCHEMBL9083981 | 0.79 | MEN1 (0.56) | DNM2PDE4AKDM4ERAB9AHTT | |
| SCHEMBL2369879 | 0.78 | DNM2 (0.49) | DNM2PTGS2KDM4EATMUSP2 | |
| SCHEMBL13950339 | 0.78 | CCR4 (0.47) | PDE4AKDM4ERAB9AHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000027826-A1 | NOVEL PYRIMIDINES, THE PRODUCTION THEREOF AND THEIR USE | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-05-18 | — | — | WO | disclosed |