Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 7/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360747 | 0.91 | F10 (0.48) | SMN1; SMN2TDP1NPC1RAB9AF10 | |
| SCHEMBL6106785 | 0.79 | F10 (0.52) | SMN1; SMN2TDP1NPC1RAB9AALDH1A1 | |
| SCHEMBL3157389 | 0.75 | RAB9A (0.62) | SMN1; SMN2TDP1NPC1RAB9AALDH1A1 | |
| SCHEMBL7357718 | 0.75 | F10 (0.45) | SMN1; SMN2TDP1NPC1RAB9AALDH1A1 | |
| SCHEMBL3157341 | 0.74 | RAB9A (0.61) | SMN1; SMN2TDP1NPC1RAB9AALDH1A1 | |
| SCHEMBL6106818 | 0.74 | F10 (0.58) | F10 | |
| SCHEMBL6106827 | 0.73 | F10 (0.52) | F10 | |
| SCHEMBL6106784 | 0.73 | F10 (0.52) | SMN1; SMN2TDP1NPC1RAB9AALDH1A1 | |
| SCHEMBL6107029 | 0.73 | F10 (0.55) | SMN1; SMN2TDP1NPC1RAB9AF10 | |
| SCHEMBL7356464 | 0.72 | F10 (0.43) | SMN1; SMN2TDP1NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140903-A1 | AROMATIC AMIDES | ELI LILLY AND COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039118-A1 | AROMATIC AMIDES | ELI LILLY AND COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |