Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7362985 | 0.91 | SMN1; SMN2 (0.46) | F10NPC1ALOX15HTTRAB9A | |
| SCHEMBL6106818 | 0.78 | F10 (0.58) | F10 | |
| SCHEMBL6592032 | 0.76 | RAB9A (0.56) | F10NPC1ALOX15HTTRAB9A | |
| SCHEMBL6107029 | 0.75 | F10 (0.55) | F10NPC1ALOX15HTTRAB9A | |
| SCHEMBL3151641 | 0.75 | SORT1 (0.61) | F10NPC1ALOX15HTTRAB9A | |
| SCHEMBL5394273 | 0.74 | F10 (0.71) | F10 | |
| SCHEMBL6107404 | 0.74 | NPC1 (0.52) | F10NPC1ALOX15HTTRAB9A | |
| SCHEMBL7360406 | 0.74 | F10 (0.48) | F10NPC1ALOX15HTTRAB9A | |
| SCHEMBL1998921 | 0.73 | F10 (0.60) | F10NPC1ALOX15HTTRAB9A | |
| SCHEMBL6107921 | 0.73 | F10 (0.52) | F10NPC1ALOX15HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140903-A1 | AROMATIC AMIDES | ELI LILLY AND COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039118-A1 | AROMATIC AMIDES | ELI LILLY AND COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |