Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.65 |
| ▸ | CTSS | P25774 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | KLK7 | P49862 | 2/20 | 0.51 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.51 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.48 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9470479 | 0.87 | PPARA (0.67) | PPARACTSSPPARGKLK7KLK5 | |
| SCHEMBL8070441 | 0.85 | PPARA (0.56) | PPARACTSSPPARGKLK7KLK5 | |
| SCHEMBL13844843 | 0.85 | PPARA (0.53) | PPARACTSSPPARGFOLH1MMP9 | |
| SCHEMBL20804457 | 0.85 | PPARA (0.53) | PPARACTSSPPARGFOLH1MMP9 | |
| SCHEMBL1414148 | 0.85 | PPARA (0.53) | PPARACTSSPPARGFOLH1MMP9 | |
| Hydrochloric Acid SCHEMBL31612159 | 0.84 | PPARA (0.52) | PPARACTSSPPARGFOLH1MMP9 | |
| Hydrochloric Acid SCHEMBL1414145 | 0.84 | PPARA (0.52) | PPARACTSSPPARGFOLH1MMP9 | |
| SCHEMBL19945248 | 0.84 | ITGA4 (0.61) | CTSSKLK5ITGA4ITGB7MMP9 | |
| SCHEMBL19945249 | 0.84 | ITGA4 (0.61) | CTSSKLK5ITGA4ITGB7MMP9 | |
| SCHEMBL17817736 | 0.83 | PPARA (0.61) | PPARACTSSPPARGFOLH1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1171116-A | N-substituted glycine derivatives as factor Xa inhibitors | CORVAS INT INC (US) | 1998-01-21 | — | — | CN | disclosed |
| EP-0801654-A1 | N-SUBSTITUTED GLYCINE DERIVATIVES AS INHIBITORS OF FACTOR Xa | CORVAS INTERNATIONAL, INC. (US) | 1997-10-22 | — | — | EP | disclosed |
| WO-1996019493-A1 | N-SUBSTITUTED GLYCINE DERIVATIVES AS INHIBITORS OF FACTOR Xa | CORVAS INTERNATIONAL, INC. (US) | 1996-06-27 | — | — | WO | disclosed |