Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.56 |
| ▸ | CTSS | P25774 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | KLK7 | P49862 | 2/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.46 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1414515 | 0.94 | PPARA (0.55) | PPARACTSSPPARGKLK7KLK5 | |
| SCHEMBL6318413 | 0.91 | PPARA (0.63) | PPARACTSSPPARGKLK7KLK5 | |
| SCHEMBL4863387 | 0.91 | PPARA (0.63) | PPARACTSSPPARGKLK7KLK5 | |
| SCHEMBL1414344 | 0.91 | PPARA (0.63) | PPARACTSSPPARGKLK7KLK5 | |
| SCHEMBL7362989 | 0.85 | PPARA (0.65) | PPARACTSSPPARGKLK7KLK5 | |
| SCHEMBL6428127 | 0.84 | ITGA4 (0.62) | CTSSKLK5ITGA4ITGB7MAPT | |
| SCHEMBL12221920 | 0.82 | ITGA4 (0.51) | CTSSITGA4ITGB7MAPTTDP1 | |
| SCHEMBL9470479 | 0.81 | PPARA (0.67) | PPARACTSSPPARGKLK7KLK5 | |
| SCHEMBL15251837 | 0.79 | MAPT (0.61) | MAPTTDP1POLBGAAXBP1 | |
| SCHEMBL15251838 | 0.79 | MAPT (0.61) | MAPTTDP1POLBGAAXBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0822180-B1 | Chelating compounds, their chelates with paramagnetic metal ions, their preparation and use | BRACCO SPA (IT) | 2000-10-25 | — | — | EP | disclosed |
| US-6099824-A | USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING | DIBRA S.P.A. (IT) | 2000-08-08 | — | — | US | disclosed |