Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 1/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 3/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 5/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367317 | 1.00 | KLK7 (0.47) | KLK7KLK5CTSLCTSSCMA1 | |
| SCHEMBL7367319 | 1.00 | KLK7 (0.47) | KLK7KLK5CTSLCTSSCMA1 | |
| SCHEMBL7363006 | 1.00 | KLK7 (0.47) | KLK7KLK5CTSLCTSSCMA1 | |
| SCHEMBL7363004 | 1.00 | KLK7 (0.47) | KLK7KLK5CTSLCTSSCMA1 | |
| SCHEMBL7307823 | 0.87 | P2RX7 (0.46) | CTSLCTSSCTSBCTSK | |
| SCHEMBL7371886 | 0.86 | P2RX7 (0.48) | CTSLCTSK | |
| SCHEMBL7371887 | 0.86 | P2RX7 (0.48) | CTSLCTSK | |
| SCHEMBL7371888 | 0.86 | P2RX7 (0.48) | CTSLCTSK | |
| SCHEMBL7297146 | 0.85 | P2RX7 (0.49) | CTSLCTSK | |
| SCHEMBL7367320 | 0.85 | KLK5 (0.45) | KLK7KLK5CTSLCMA1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242600-B1 | ANTIISCHEMIC AGENTS, ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-0970071-A1 | 2-PEPERAZINONE-1-ACETIC ACID DERIVATIVES AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998039324-A1 | 2-PEPERAZINONE-1-ACETIC ACID DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-11 | — | — | WO | disclosed |