Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | USP5 | P45974 | 4/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7846676 | 0.83 | PIK3CD (0.35) | SMN1; SMN2ALDH1A1KDM4ELMNATSHR | |
| SCHEMBL7735410 | 0.83 | ALDH1A1 (0.40) | ALDH1A1KDM4EMEN1LMNAHTT | |
| SCHEMBL20504425 | 0.79 | NR1H2 (0.36) | HTTCA12CA1CA2CA7 | |
| SCHEMBL5760564 | 0.78 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1KDM4EMEN1LMNA | |
| SCHEMBL6952517 | 0.77 | ALDH1A1 (0.35) | ALDH1A1KDM4EMEN1LMNATSHR | |
| SCHEMBL9857179 | 0.77 | TSHR (0.35) | SMN1; SMN2ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL9857832 | 0.77 | TSHR (0.35) | SMN1; SMN2ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL9239762 | 0.77 | S1PR3 (0.39) | ALDH1A1MEN1HTTKMT2AHDAC6 | |
| SCHEMBL9239760 | 0.77 | S1PR3 (0.39) | ALDH1A1MEN1HTTKMT2AHDAC6 | |
| SCHEMBL26641101 | 0.76 | SNCA (0.36) | ALDH1A1LMNAMAPK1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204652-A1 | NOVEL SUCCINATE DERIVATIVE COMPOUNDS USEFUL AS CYSTEINE PROTEASE INHIBITORS | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001009110-A1 | NOVEL SUCCINATE DERIVATIVE COMPOUNDS USEFUL AS CYSTEINE PROTEASE INHIBITORS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2001-02-08 | — | — | WO | disclosed |