Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735410 | 0.88 | ALDH1A1 (0.40) | CA1CA2CA12CA7CA14 | |
| SCHEMBL20504425 | 0.84 | NR1H2 (0.36) | CA1CA2CA12CA7CA14 | |
| SCHEMBL7363379 | 0.83 | SMN1; SMN2 (0.41) | CA1CA2CA12CA7CA14 | |
| SCHEMBL6952517 | 0.82 | ALDH1A1 (0.35) | ALDH1A1GAALMNAHTTMCOLN3 | |
| SCHEMBL9239762 | 0.82 | S1PR3 (0.39) | ALDH1A1GAAMAPTCYP3A4HTT | |
| SCHEMBL9239760 | 0.82 | S1PR3 (0.39) | ALDH1A1GAAMAPTCYP3A4HTT | |
| SCHEMBL26641101 | 0.81 | SNCA (0.36) | PIK3CDCA1CA2PIK3CGPIK3CB | |
| SCHEMBL2484523 | 0.80 | PIK3CD (0.36) | PIK3CDPIK3CGPIK3CBALDH1A1CYP3A4 | |
| SCHEMBL6952509 | 0.79 | ALDH1A1 (0.36) | CA1CA2CA7ALDH1A1LMNA | |
| SCHEMBL4503612 | 0.78 | HTT (0.33) | ALDH1A1GAALMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150991-A2 | COMPOSITIONS FOR TREATING INFLAMMATORY RESPONSE | THE UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000044763-A2 | COMPOSITIONS FOR TREATING INFLAMMATORY RESPONSE | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2000-08-03 | — | — | WO | disclosed |