Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7366809 | 0.88 | PDE4A (0.64) | PDE4AKCNH2 | |
| SCHEMBL7393300 | 0.84 | PDE4A (0.52) | PDE4AKCNH2 | |
| SCHEMBL7991197 | 0.80 | PDE4A (0.58) | PDE4AKCNH2 | |
| SCHEMBL7366254 | 0.78 | PDE4A (0.64) | PDE4AKCNH2 | |
| SCHEMBL7359822 | 0.77 | PDE4A (0.66) | PDE4AKCNH2 | |
| SCHEMBL7908346 | 0.77 | PDE4A (0.67) | PDE4AKCNH2 | |
| SCHEMBL7907997 | 0.77 | PDE4A (0.74) | PDE4AKCNH2 | |
| SCHEMBL7905272 | 0.77 | PDE4A (0.69) | PDE4AKCNH2 | |
| SCHEMBL7906831 | 0.76 | PDE4A (0.59) | PDE4AKCNH2 | |
| SCHEMBL7364231 | 0.76 | PDE4A (0.51) | PDE4AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189888-A1 | HETEROSUBSTITUTED PYRIDINE DERIVATIVES AS $i(PDE 4) INHIBITORS | Merck Frosst Canada & Co. (CA) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000069824-A1 | HETEROSUBSTITUTED PYRIDINE DERIVATIVES AS PDE 4 INHIBITORS | MERCK FROSST CANADA & CO. (CA) | 2000-11-23 | — | — | WO | disclosed |