Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5942728 | 0.88 | PDE4A (0.52) | PDE4AKCNH2 | |
| SCHEMBL7907997 | 0.86 | PDE4A (0.74) | PDE4AKCNH2 | |
| SCHEMBL7397686 | 0.82 | PDE4A (0.61) | PDE4AKCNH2 | |
| SCHEMBL6887744 | 0.81 | PDE4A (0.77) | PDE4A | |
| SCHEMBL6887748 | 0.81 | PDE4A (0.77) | PDE4A | |
| SCHEMBL7899116 | 0.80 | PDE4A (0.70) | PDE4A | |
| SCHEMBL7906783 | 0.80 | PDE4A (0.78) | PDE4A | |
| SCHEMBL7905253 | 0.79 | PDE4A (0.78) | PDE4AKCNH2 | |
| SCHEMBL7991197 | 0.79 | PDE4A (0.58) | PDE4AKCNH2 | |
| SCHEMBL7379831 | 0.79 | PDE4A (0.58) | PDE4AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316472-B1 | Heterosubstituted pyridine derivatives as PDE 4 inhibitors | MERCK FROSST CANADA & CO. (CA) | 2001-11-13 | — | — | US | disclosed |
| US-6200993-B1 | ASTHMA; ANTIINFLAMMATORY AGENTS | MERCK FROSST CANADA & CO. (CA) | 2001-03-13 | — | — | US | disclosed |
| US-6180650-B1 | ANTIINFLAMMATORY AGENTS; RESPIRATORY SYSTEM DISORDERS; SKIN DISORDERS; ANTITUMOR AGENTS | MERCK FROSST CANADA & CO. (CA) | 2001-01-30 | — | — | US | disclosed |