Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 14/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 6/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 7/20 | 0.42 |
| ▸ | REN | P00797 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7387789 | 0.86 | MMP1 (0.41) | MMP1MMP3MMP2MMP9REN | |
| SCHEMBL7357542 | 0.85 | MMP1 (0.55) | MMP1MMP3MMP2MMP9 | |
| SCHEMBL7353371 | 0.85 | ERAP1 (0.53) | MMP2MMP9 | |
| SCHEMBL7322307 | 0.84 | MMP1 (0.48) | MMP1MMP3MMP2MMP9REN | |
| SCHEMBL7324452 | 0.83 | MMP1 (0.45) | MMP1MMP3MMP2MMP9 | |
| SCHEMBL9348262 | 0.83 | MMP1 (0.51) | MMP1MMP3MMP2MMP9REN | |
| SCHEMBL7322384 | 0.83 | MMP1 (0.54) | MMP1MMP3MMP2MMP9REN | |
| SCHEMBL7356800 | 0.82 | ERAP1 (0.53) | CTSKMMP2MMP9 | |
| SCHEMBL7353015 | 0.81 | MMP1 (0.38) | MMP1MMP3MMP2MMP9REN | |
| SCHEMBL7328452 | 0.81 | MMP1 (0.45) | MMP1MMP3MMP2MMP9REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995013817-A1 | ENDOTHELIN CONVERTING ENZYME INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-05-26 | — | — | WO | disclosed |