Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.60 |
| ▸ | F2 | P00734 | 14/20 | 0.60 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7463474 | 0.94 | F2 (0.54) | F10F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL8347672 | 0.88 | F2 (0.54) | F10F2PRSS1 | |
| Benzamidine SCHEMBL7366537 | 0.86 | F10 (0.67) | F10F2PRSS1 | |
| Methyl Benzoate SCHEMBL7359033 | 0.82 | F10 (0.61) | F10F2PRSS1 | |
| 4-Methylbenzimidamide SCHEMBL7357637 | 0.80 | F10 (0.65) | F10F2PRSS1 | |
| SCHEMBL7366288 | 0.79 | F10 (0.64) | F10F2PRSS1 | |
| SCHEMBL7456785 | 0.79 | F10 (0.71) | F10F2PRSS1 | |
| Benzamide SCHEMBL7364697 | 0.78 | F10 (0.55) | F10F2PRSS1 | |
| Methyl Benzoate SCHEMBL7560351 | 0.77 | F2 (0.55) | F10F2PRSS1 | |
| Benzamidine SCHEMBL7359774 | 0.75 | F10 (0.54) | F10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030971-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |