Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7362906 | 0.88 | PPARG (0.34) | LPAR1ITGB1ITGA4PPARGPPARA | |
| SCHEMBL7365143 | 0.88 | MMP12 (0.37) | LPAR1ITGB1ITGA4PPARGPPARA | |
| SCHEMBL7361146 | 0.82 | F2 (0.40) | MMP3CA1CA2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7361555 | 0.81 | F2 (0.39) | MMP3CA1CA2ALDH1A1SPHK1 | |
| SCHEMBL7363933 | 0.77 | F2 (0.36) | CA1CA2ALDH1A1 | |
| SCHEMBL7361085 | 0.75 | PPARG (0.36) | ITGB1PPARGPPARACA1CA2 | |
| SCHEMBL7367192 | 0.72 | F10 (0.42) | CA1CA2 | |
| SCHEMBL7368444 | 0.72 | FFAR1 (0.41) | PPARGPPARA | |
| Trifluoroacetic Acid SCHEMBL7458550 | 0.72 | F2 (0.41) | ALDH1A1 | |
| SCHEMBL7360137 | 0.71 | CA1 (0.36) | PPARGCA1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-B1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2002-11-20 | — | — | EP | claimed |
| EP-0892780-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-01-27 | — | — | EP | claimed |
| WO-1997030971-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-28 | — | — | WO | claimed |
| EP-0892780-B1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2002-11-20 | — | — | EP | disclosed |