Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.50 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.50 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25449209 | 0.84 | AKR1C3 (0.66) | AKR1C3AKR1C2PDK1PDK2PDK3 | |
| SCHEMBL522766 | 0.82 | AKR1C3 (0.50) | AKR1C3AKR1C2PDK1PDK2PDK3 | |
| SCHEMBL848499 | 0.82 | POLB (0.64) | AKR1C3AKR1C2PDK1PDK2PDK3 | |
| SCHEMBL31087257 | 0.82 | POLB (0.64) | AKR1C3AKR1C2PDK1PDK2PDK3 | |
| SCHEMBL27900539 | 0.82 | AKR1C3 (0.50) | AKR1C3AKR1C2PDK1PDK2PDK3 | |
| SCHEMBL20219732 | 0.80 | AKR1C3 (0.49) | AKR1C3AKR1C2PDK1PDK2PDK3 | |
| SCHEMBL29808973 | 0.80 | CYP2C19 (0.69) | PDK1PDK2PDK3PDK4CNR2 | |
| SCHEMBL6857308 | 0.80 | NPC1 (0.57) | AKR1C3AKR1C2PDK1PDK2PDK3 | |
| SCHEMBL505353 | 0.80 | CYP2C19 (0.69) | PDK1PDK2PDK3PDK4CNR2 | |
| Hydrochloric Acid SCHEMBL15974089 | 0.80 | POLB (0.62) | AKR1C3AKR1C2PDK1PDK2PDK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0966433-B1 | PREPARATION OF N-ARYL-N-HYDROXAMIDES | CONSORTIUM ELEKTROCHEM IND (DE) | 2002-05-22 | — | — | EP | disclosed |
| US-6232492-B1 | REACTING ARYLHYDROXYLAMINE WITH A KETENE | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 2001-05-15 | — | — | US | disclosed |
| EP-0966433-A1 | PREPARATION OF N-ARYL-N-HYDROXAMIDES | Consortium für elektrochemische Industrie GmbH (DE) | 1999-12-29 | — | — | EP | disclosed |
| WO-1998038159-A1 | PREPARATION OF N-ARYL-N-HYDROXAMIDES | Consortium für elektrochemische Industrie GmbH (DE) | 1998-09-03 | — | — | WO | disclosed |
| US-4657906-A | CARDIOVASCULAR DISORDERS | SMITH KLINE & FRENCH LABORATORIES LTD. (GB) | 1987-04-14 | — | — | US | disclosed |
| US-4556711-A | CARDIOTONIC AGENTS | SMITH KLINE & FRENCH LABORATORIES LTD. (US) | 1985-12-03 | — | — | US | disclosed |
| EP-0096517-A2 | Aryl pyrazinones | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1983-12-21 | — | — | EP | disclosed |