Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.50 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.50 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31087257 | 1.00 | POLB (0.64) | POLBKDM4EATMAKR1C3AKR1C2 | |
| Hydrochloric Acid SCHEMBL15974089 | 0.98 | POLB (0.62) | POLBKDM4EATMAKR1C3AKR1C2 | |
| SCHEMBL13252224 | 0.88 | POLB (0.56) | POLBKDM4EATMAKR1C3AKR1C2 | |
| SCHEMBL25449209 | 0.84 | AKR1C3 (0.66) | POLBKDM4EAKR1C3AKR1C2PDK1 | |
| SCHEMBL8628627 | 0.84 | POLB (0.67) | POLBKDM4EATMAKR1C3CYP2C19 | |
| SCHEMBL28818947 | 0.83 | AKR1C3 (0.47) | POLBKDM4EATMAKR1C3AKR1C2 | |
| SCHEMBL27723917 | 0.83 | POLB (0.60) | POLBKDM4EATMCYP2C19ALDH1A1 | |
| N-Methylanthranilic Acid SCHEMBL130356 | 0.82 | KDM4E (0.64) | POLBKDM4EATMAKR1C3AKR1C2 | |
| SCHEMBL6964053 | 0.82 | KDM4E (0.64) | POLBKDM4EATMCYP2C19ALDH1A1 | |
| N-Methylanthranilic Acid SCHEMBL29381752 | 0.82 | KDM4E (0.64) | POLBKDM4EATMAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | claimed |
| EP-3229612-B1 | USE OF FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME | MARS INC (US) | 2024-06-26 | — | — | EP | disclosed |
| WO-2024091450-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-05-02 | — | — | WO | disclosed |
| US-20230255933-A1 | ANTIVIRAL USE OF FABP4 MODULATING COMPOUNDS | CRESCENTA BIOSCIENCES (US) | 2023-08-17 | — | — | US | disclosed |
| US-20230137773-A1 | RAS INHIBITORY PEPTIDES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2023-05-04 | — | — | US | disclosed |
| US-20230137773-A1 | RAS INHIBITORY PEPTIDES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2023-05-04 | — | — | US | disclosed |
| US-11377476-B2 | Ras inhibitory peptides and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-07-05 | — | — | US | disclosed |
| WO-2022118186-A1 | SENOTHERAPEUTIC COMPOUND | BIONEXA S.R.L. (IT) | 2022-06-09 | — | — | WO | disclosed |
| EP-3943108-A1 | ANTIGEN-BINDING MOLECULE CONTAINING ANTIGEN-BINDING DOMAIN OF WHICH BINDING ACTIVITY TO ANTIGEN IS CHANGED DEPENDING ON MTA, AND LIBRARY FOR OBTAINING SAID ANTIGEN-BINDING DOMAIN | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2022-01-26 | — | — | EP | disclosed |
| EP-3206689-B1 | INHIBITORS OF LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE AND USES THEREOF | LA JOLLA INST OF ALLERGY & IMMUNOLOGY (US) | 2021-12-08 | — | — | EP | disclosed |
| US-4997840-A | Quinolone sulphonates having antihypertensive activity | THE BOOTS COMPANY, PLC (GB) | 1991-03-05 | — | — | US | disclosed |
| EP-0330340-A1 | Therapeutic agents | The Boots Company PLC (GB) | 1989-08-30 | — | — | EP | disclosed |
| WO-1989007593-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1989-08-24 | — | — | WO | disclosed |
| US-4414416-A | Certain diacetyl-amino-phenolic derivatives | FISONS LIMITED (GB) | 1983-11-08 | — | — | US | disclosed |
| US-4328341-A | Process for preparing certain pyrano[3,2-g]quinoline 2,8-dicarboxylates and 4-oxo-quinoline-2-carboxylates | FISONS LIMITED (GB) | 1982-05-04 | — | — | US | disclosed |
| EP-0030423-A1 | A process for the production of 1,4-dihydro-4-oxo-quinoline-2-carboxylic acids, or salts, esters or amides thereof and intermediates therefor | FISONS plc (GB) | 1981-06-17 | — | — | EP | disclosed |
| US-4198496-A | COBALT COMPONENT, MAGNESIUM OR MANGANESE CHLORIDE, IODIDE OR CARBOXYLIC ACID SATL, ORGANOALUMINUM HALIDE AS CATALYST | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1980-04-15 | — | — | US | disclosed |
| US-4051308-A | Process for polymerizing butadiene with cobalt complex, AlR3 and CS2 | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1977-09-27 | — | — | US | disclosed |
| US-3993856-A | CATALYST OF COBALT COMPOUND, HYDRO- OR HYDROCARBYLALUMINUM DIHALIDE, AND CARBON DISULFIDE | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1976-11-23 | — | — | US | disclosed |
| US-3956390-A | Preparation of amines | SCHERING CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230137773-A1 | RAS INHIBITORY PEPTIDES AND USES THEREOF | TPX2, RASGRP1, KRAS | POLB 4522/4885KDM4E 4235/4885ATM 4654/4885 |
| US-20230255933-A1 | ANTIVIRAL USE OF FABP4 MODULATING COMPOUNDS | FABP1, FABP4, FABP5 | POLB 3010/4885KDM4E 1451/4885ATM 4851/4885 |
| US-11377476-B2 | Ras inhibitory peptides and uses thereof | KRAS, RASGRP1, RASGRP3 | POLB 3990/4885KDM4E 3376/4885ATM 4701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.