Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 10/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19125588 | 0.79 | THRB (0.64) | ALDH1A1L3MBTL1THRBMAPTLMNA | |
| SCHEMBL7367801 | 0.74 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1THRBMAPTLMNA | |
| SCHEMBL13800968 | 0.73 | MAPT (0.68) | ALDH1A1THRBMAPTLMNASMN1; SMN2 | |
| SCHEMBL31670390 | 0.73 | MAPT (0.68) | ALDH1A1THRBMAPTLMNASMN1; SMN2 | |
| SCHEMBL10592497 | 0.70 | MEN1 (0.45) | ALDH1A1MAPTLMNASMN1; SMN2MAPK1 | |
| SCHEMBL8956720 | 0.68 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1THRBMAPTLMNA | |
| SCHEMBL17717719 | 0.68 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL11147739 | 0.68 | ALDH1A1 (0.70) | ALDH1A1L3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL11110100 | 0.68 | ELANE (0.67) | ALDH1A1L3MBTL1THRBMAPTLMNA | |
| SCHEMBL11820694 | 0.68 | MEN1 (0.46) | ALDH1A1L3MBTL1THRBMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018764-A1 | DIHYDROBENZOANTHRACENONE, -PYRIMIDINONE OR DIHYDRONAPHTOQUINOLINONE | MERCK PATENT GMBH (DE) | 1998-05-07 | — | — | WO | disclosed |