Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 8/20 | 0.41 |
| ▸ | TMPRSS6 | Q8IU80 | 4/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | PROC | P04070 | 1/20 | 0.41 |
| ▸ | TMPRSS11D | O60235 | 8/20 | 0.40 |
| ▸ | HPN | P05981 | 1/20 | 0.39 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | PLG | P00747 | 2/20 | 0.39 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7362868 | 1.00 | F2 (0.41) | F2TMPRSS6ITGB3ITGA2BPROC | |
| SCHEMBL8019344 | 0.97 | ITGB3 (0.44) | F2TMPRSS6ITGB3ITGA2BPROC | |
| SCHEMBL7362891 | 0.87 | F2 (0.44) | F2TMPRSS6PROCTMPRSS11DHPN | |
| SCHEMBL7355230 | 0.87 | F2 (0.44) | F2TMPRSS6PROCTMPRSS11DHPN | |
| SCHEMBL8023156 | 0.86 | F2 (0.48) | F2TMPRSS6PROCTMPRSS11DF10 | |
| SCHEMBL7362804 | 0.86 | F2 (0.44) | F2TMPRSS6PROCTMPRSS11DHPN | |
| SCHEMBL7356268 | 0.81 | HPN (0.59) | F2PROCHPNST14F10 | |
| SCHEMBL8770719 | 0.79 | TMPRSS11D (0.62) | F2TMPRSS11DF10PLG | |
| SCHEMBL8781243 | 0.77 | F2 (0.40) | F2TMPRSS6PROCHPNST14 | |
| SCHEMBL7365085 | 0.76 | TMPRSS11D (0.64) | F2TMPRSS11DF10PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0796271-B1 | DIPEPTIDE P-AMIDINOBENZYLAMIDES WITH N-TERMINAL SULFONYL OR AMINOSULFONYL RADICALS | BASF AG (DE) | 2000-02-02 | — | — | EP | disclosed |
| WO-1996017860-A1 | NEW DIPEPTIDE P-AMIDINOBENZYLAMIDES WITH N-TERMINAL SULFONYL OR AMINOSULFONYL RADICALS | BASF AKTIENGESELLSCHAFT (DE) | 1996-06-13 | — | — | WO | disclosed |