Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 12/20 | 0.44 |
| ▸ | TMPRSS6 | Q8IU80 | 4/20 | 0.44 |
| ▸ | PROC | P04070 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 2/20 | 0.42 |
| ▸ | HPN | P05981 | 1/20 | 0.40 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.40 |
| ▸ | TMPRSS11D | O60235 | 2/20 | 0.39 |
| ▸ | F3 | P13726 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7362891 | 0.90 | F2 (0.44) | F2TMPRSS6PROCF7HPN | |
| SCHEMBL7355230 | 0.90 | F2 (0.44) | F2TMPRSS6PROCHPNHGFAC | |
| SCHEMBL8019344 | 0.87 | ITGB3 (0.44) | F2TMPRSS6PROCTMPRSS11D | |
| SCHEMBL8023156 | 0.86 | F2 (0.48) | F2TMPRSS6PROCTMPRSS11D | |
| SCHEMBL7362868 | 0.86 | F2 (0.41) | F2TMPRSS6PROCHPNST14 | |
| SCHEMBL7364257 | 0.86 | F2 (0.41) | F2TMPRSS6PROCHPNST14 | |
| SCHEMBL7356268 | 0.84 | HPN (0.59) | F2PROCHPNHGFACST14 | |
| SCHEMBL8781243 | 0.80 | F2 (0.40) | F2TMPRSS6PROCF7HPN | |
| SCHEMBL7357020 | 0.71 | F2 (0.53) | F2TMPRSS6HPNHGFACST14 | |
| SCHEMBL8727239 | 0.70 | F2 (0.46) | F2TMPRSS6PROCF7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0796271-B1 | DIPEPTIDE P-AMIDINOBENZYLAMIDES WITH N-TERMINAL SULFONYL OR AMINOSULFONYL RADICALS | BASF AG (DE) | 2000-02-02 | — | — | EP | disclosed |
| EP-0796271-A1 | NEW DIPEPTIDE P-AMIDINOBENZYLAMIDES WITH N-TERMINAL SULFONYL OR AMINOSULFONYL RADICALS | BASF AKTIENGESELLSCHAFT (DE) | 1997-09-24 | — | — | EP | disclosed |
| WO-1996017860-A1 | NEW DIPEPTIDE P-AMIDINOBENZYLAMIDES WITH N-TERMINAL SULFONYL OR AMINOSULFONYL RADICALS | BASF AKTIENGESELLSCHAFT (DE) | 1996-06-13 | — | — | WO | disclosed |