Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.56 |
| ▸ | HPGDS | O60760 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20170935 | 0.84 | HPGDS (0.61) | HDAC1HDAC3HPGDSHPGDCYP1A2 | |
| SCHEMBL3547707 | 0.84 | HPGDS (0.61) | HDAC1HDAC3HPGDSHPGDCYP1A2 | |
| SCHEMBL7366253 | 0.80 | HDAC1 (0.64) | HDAC1HDAC2HDAC3HDAC6HDAC8 | |
| SCHEMBL7365399 | 0.80 | HDAC1 (0.61) | HDAC1HDAC2HDAC3HDAC6HDAC8 | |
| SCHEMBL3436271 | 0.79 | HPGD (0.66) | HDAC1HPGDSHPGDCYP1A2CYP3A4 | |
| SCHEMBL27966332 | 0.79 | HPGD (0.66) | HDAC1HDAC3HPGDSHPGDCYP1A2 | |
| SCHEMBL13407997 | 0.77 | HPGD (0.77) | HDAC1HPGDSHPGDCYP1A2CYP3A4 | |
| SCHEMBL26453259 | 0.77 | HPGD (0.63) | HDAC1HDAC3HPGDSHPGDCYP1A2 | |
| SCHEMBL7368674 | 0.77 | HDAC1 (0.80) | HDAC1HDAC2HDAC3HDAC6HDAC8 | |
| SCHEMBL12789158 | 0.76 | HPGD (0.69) | HDAC1HDAC2HPGDSHPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020177594-A1 | Inhibitors of histone deacetylase | ABBOTT LABORATORIES | 2002-11-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020177594-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC11, HDAC3 | HDAC1 1/4885HDAC2 4/4885HDAC3 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.