Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 4/20 | 0.56 |
| ▸ | CTSE | P14091 | 1/20 | 0.56 |
| ▸ | PGC | P20142 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | REN | P00797 | 2/20 | 0.52 |
| ▸ | BACE1 | P56817 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364428 | 1.00 | CTSD (0.56) | CTSDCTSEPGCCA2REN | |
| SCHEMBL7279589 | 0.94 | CA2 (0.56) | CTSDCTSEPGCCA2REN | |
| Hydrochloric Acid SCHEMBL8536656 | 0.82 | CTSD (0.58) | CTSDCTSEPGCCA2BACE1 | |
| Hydrochloric Acid SCHEMBL8531698 | 0.82 | CTSD (0.58) | CTSDCTSEPGCCA2BACE1 | |
| Hydrochloric Acid SCHEMBL8531904 | 0.82 | CTSD (0.58) | CTSDCTSEPGCCA2BACE1 | |
| Hydrochloric Acid SCHEMBL8534600 | 0.82 | CTSD (0.58) | CTSDCTSEPGCCA2BACE1 | |
| Hydrochloric Acid SCHEMBL8536396 | 0.82 | CTSD (0.58) | CTSDCTSEPGCCA2BACE1 | |
| Hydrochloric Acid SCHEMBL8534880 | 0.82 | CTSD (0.58) | CTSDCTSEPGCCA2BACE1 | |
| SCHEMBL24322664 | 0.82 | CTSD (0.56) | CTSDCTSEPGCBACE1 | |
| SCHEMBL7335443 | 0.81 | CA2 (0.52) | CTSDCTSEPGCCA2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415981-A4 | RETROVIRAL PROTEASE INHIBITORS | — | 1991-10-09 | — | — | EP | disclosed |
| EP-0415981-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0342541-A2 | Retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1989-11-23 | — | — | EP | disclosed |
| WO-1989010752-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |