Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 8/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11177938 | 0.74 | FFAR1 (0.45) | CHRM3CHRM2CHRM1KEAP1NFE2L2 | |
| SCHEMBL17923217 | 0.72 | CHRM2 (0.38) | CHRM3CHRM2CHRM1LMNAKEAP1 | |
| SCHEMBL17923185 | 0.72 | ALDH1A1 (0.43) | CHRM3CHRM2CHRM1KEAP1NFE2L2 | |
| SCHEMBL17923226 | 0.72 | CHRM2 (0.38) | CHRM3CHRM2CHRM1LMNAKEAP1 | |
| SCHEMBL17941193 | 0.72 | CHRM2 (0.38) | CHRM3CHRM2CHRM1LMNAKEAP1 | |
| SCHEMBL18040347 | 0.72 | ALDH1A1 (0.43) | CHRM3CHRM2CHRM1KEAP1NFE2L2 | |
| SCHEMBL10519057 | 0.71 | ELANE (0.42) | CHRM3CHRM2CHRM1LMNAKEAP1 | |
| SCHEMBL30899499 | 0.71 | CHRM2 (0.40) | CHRM3CHRM2CHRM1LMNAKEAP1 | |
| SCHEMBL1802808 | 0.71 | ELANE (0.42) | CHRM3CHRM2CHRM1LMNAKEAP1 | |
| SCHEMBL17923208 | 0.69 | CYP2D6 (0.41) | CHRM3CHRM2CHRM1LMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042656-A1 | NOVEL COMPOUNDS | CYTEL CORPORATION (US) | 1998-10-01 | — | — | WO | disclosed |