Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.56 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.56 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.56 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.56 |
| ▸ | FAP | Q12884 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7365105 | 0.99 | DPP4 (0.55) | DPP4DPP7DPP8DPP9FAP | |
| Hydrochloric Acid SCHEMBL7365110 | 0.99 | DPP4 (0.55) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL7365154 | 0.87 | DPP4 (0.55) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL7363744 | 0.84 | OPRD1 (0.61) | DPP4OPRD1OPRK1 | |
| SCHEMBL7361820 | 0.84 | DPP4 (0.52) | DPP4DPP7DPP8DPP9OPRD1 | |
| SCHEMBL7361154 | 0.81 | AKT1 (0.49) | DPP4OPRD1KMT2AOPRK1 | |
| SCHEMBL7440658 | 0.81 | DPP4 (0.57) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL13713047 | 0.76 | SMN1; SMN2 (0.54) | GAAALDH1A1LMNAHTTMEN1 | |
| SCHEMBL4796631 | 0.76 | HDAC8 (0.71) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL4771058 | 0.76 | HDAC8 (0.71) | DPP4DPP7DPP8DPP9FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046553-A1 | THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | disclosed |