Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.52 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.52 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.52 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363744 | 0.90 | OPRD1 (0.61) | DPP4OPRD1OPRK1SMYD3 | |
| SCHEMBL7361154 | 0.86 | AKT1 (0.49) | DPP4OPRD1OPRK1AKT1SMYD3 | |
| SCHEMBL7440658 | 0.86 | DPP4 (0.57) | DPP4DPP8DPP9DPP7OPRD1 | |
| SCHEMBL7367542 | 0.86 | DPP4 (0.51) | DPP4DPP8DPP9DPP7OPRD1 | |
| SCHEMBL7366936 | 0.85 | DPP4 (0.50) | DPP4DPP8DPP9DPP7OPRD1 | |
| SCHEMBL7364592 | 0.84 | DPP4 (0.56) | DPP4DPP8DPP9DPP7OPRD1 | |
| Hydrochloric Acid SCHEMBL7365105 | 0.83 | DPP4 (0.55) | DPP4DPP8DPP9DPP7OPRD1 | |
| Hydrochloric Acid SCHEMBL7365110 | 0.83 | DPP4 (0.55) | DPP4DPP8DPP9DPP7OPRD1 | |
| SCHEMBL5359350 | 0.76 | DPP4 (0.57) | DPP4DPP8DPP9DPP7AKT1 | |
| SCHEMBL2375476 | 0.76 | OPRK1 (0.71) | DPP4OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046553-A1 | THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | disclosed |