Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ACE | P12821 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | PREP | P48147 | 4/20 | 0.43 |
| ▸ | FAP | Q12884 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8476331 | 0.85 | MAPK8 (0.52) | ALDH1A1ACELMNAKCNK3PREP | |
| SCHEMBL7369918 | 0.85 | MAPK8 (0.52) | ALDH1A1ACELMNAKCNK3PREP | |
| SCHEMBL7363975 | 0.84 | CYP2C19 (0.52) | ALDH1A1SMN1; SMN2ACELMNAKCNK3 | |
| SCHEMBL7361372 | 0.84 | ACE (0.45) | ALDH1A1KMT2ASMN1; SMN2ACELMNA | |
| SCHEMBL7368109 | 0.83 | PREP (0.43) | ALDH1A1SMN1; SMN2ACELMNAKCNK3 | |
| SCHEMBL7366700 | 0.77 | ACE (0.50) | ALDH1A1SMN1; SMN2ACELMNAPREP | |
| SCHEMBL8720975 | 0.76 | ACE (0.45) | ALDH1A1SMN1; SMN2ACELMNAKCNK3 | |
| SCHEMBL7369394 | 0.76 | SMYD3 (0.50) | ALDH1A1SMN1; SMN2ACELMNAKCNK3 | |
| SCHEMBL7368017 | 0.76 | ACE (0.47) | ALDH1A1SMN1; SMN2ACELMNAKCNK3 | |
| SCHEMBL7366766 | 0.74 | PREP (0.66) | ALDH1A1SMN1; SMN2ACELMNAKCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500989-B1 | N-(alpha-substituted-pyridinyl) carbonyl dipeptide antihypertensive agents | LACER SA (ES) | 1998-12-09 | — | — | EP | disclosed |
| US-5432159-A | N-(α-substituted-pyridinyl)carbonyl dipeptide antihypertensive agents | LACER S.A. (ES) | 1995-07-11 | — | — | US | disclosed |
| WO-1992015608-A1 | N-(α-SUBSTITUTED-PYRIDINYL)CARBONYL DIPEPTIDE ANTIHYPERTENSIVE AGENTS | LACER S.A. (ES) | 1992-09-17 | — | — | WO | disclosed |
| EP-0500989-A1 | N-(alpha-substituted-pyridinyl) carbonyl dipeptide antihypertensive agents | LACER, S.A. (ES) | 1992-09-02 | — | — | EP | disclosed |