Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30172716 | 0.84 | LMNA (0.61) | LMNATSHRPDE2ATRPA1ADRB2 | |
| SCHEMBL5107130 | 0.84 | LMNA (0.61) | LMNATSHRPDE2ATRPA1ADRB2 | |
| SCHEMBL5107133 | 0.84 | LMNA (0.61) | LMNATSHRPDE2ATRPA1ADRB2 | |
| SCHEMBL5107136 | 0.84 | LMNA (0.61) | LMNATSHRPDE2ATRPA1ADRB2 | |
| SCHEMBL9219679 | 0.82 | LMNA (0.33) | LMNATSHRTRPA1ADRB2ADRB1 | |
| SCHEMBL814926 | 0.77 | TSHR (0.40) | LMNATSHRTRPA1GABRA1GABRB2 | |
| SCHEMBL5907398 | 0.77 | LMNA (0.54) | LMNATSHRPDE2ATRPA1ADRB2 | |
| SCHEMBL593087 | 0.76 | LMNA (0.52) | LMNATSHRPDE2ATRPA1ADRB2 | |
| SCHEMBL2990957 | 0.76 | TSHR (0.65) | LMNATSHRPDE2ATRPA1ADRB1 | |
| SCHEMBL28639572 | 0.76 | LMNA (0.52) | LMNATSHRPDE2ATRPA1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815108-A1 | CYCLIC UREA HIV PROTEASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-01-07 | — | — | EP | claimed |
| WO-1996029329-A1 | CYCLIC UREA HIV PROTEASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-26 | — | — | WO | claimed |
| US-9074021-B2 | Cellulose derivative, thermo-molding material, molded body and method for preparation thereof, and case for electric and electronic devices | FUJIFILM CORPORATION (JP) | 2015-07-07 | — | — | US | disclosed |
| EP-2465899-B1 | CELLULOSE DERIVATIVE, THERMOFORMED MATERIAL, MOLDED BODY, PRODUCTION METHOD THEREFOR, AND CASING FOR ELECTRICAL AND ELECTRONIC EQUIPMENT | FUJIFILM CORP (JP) | 2014-11-05 | — | — | EP | disclosed |
| US-20120165517-A1 | CELLULOSE DERIVATIVE, THERMO-MOLDING MATERIAL, MOLDED BODY AND METHOD FOR PREPARATION THEREOF, AND CASE FOR ELECTRIC AND ELECTRONIC DEVICES | FUJIFILM CORPORATION (JP) | 2012-06-28 | — | — | US | disclosed |
| EP-2465899-A1 | CELLULOSE DERIVATIVE, THERMOFORMED MATERIAL, MOLDED BODY, PRODUCTION METHOD THEREFOR, AND CASING FOR ELECTRICAL AND ELECTRONIC EQUIPMENT | FUJIFILM Corporation (JP) | 2012-06-20 | — | — | EP | disclosed |
| WO-1996029329-A1 | CYCLIC UREA HIV PROTEASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-26 | — | — | WO | disclosed |
| US-4831041-A | ANTIULCER AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0268989-A1 | Imidazopyridine compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-01 | — | — | EP | disclosed |