Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 12/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL7318816 | 0.95 | SMN1; SMN2 (0.47) | ACELMNASMN1; SMN2ABCB11POLB | |
| SCHEMBL9394613 | 0.89 | ACE (0.40) | ACEALDH1A1 | |
| SCHEMBL7266941 | 0.87 | ACE (0.42) | ACELMNAPOLBALDH1A1 | |
| SCHEMBL8715043 | 0.78 | ACE (0.49) | ACELMNASMN1; SMN2ABCB11MEN1 | |
| SCHEMBL5551908 | 0.76 | DPP8 (0.40) | ACE | |
| SCHEMBL10883512 | 0.75 | DPP7 (0.39) | ACE | |
| SCHEMBL8568423 | 0.75 | ACE (0.45) | ACELMNASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL10696084 | 0.75 | ACE (0.45) | ACELMNASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL649164 | 0.74 | DPP8 (0.43) | ACE | |
| SCHEMBL5552493 | 0.74 | DPP8 (0.43) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0523449-B1 | Reductive amination of an aminoacid or an aminoacid derivative with an alpha-keto acid or an alpha-keto acid derivative | DEGUSSA (DE) | 1996-05-15 | — | — | EP | disclosed |
| EP-0523449-A2 | Reductive amination of an aminoacid or an aminoacid derivative with an alpha-keto acid or an alpha-keto acid derivative | DEGUSSA AG (DE) | 1993-01-20 | — | — | EP | disclosed |
| EP-0012401-A1 | Carboxyalkyl dipeptide derivatives, process for preparing them and pharmaceutical composition containing them | MERCK & CO. INC. (US) | 1980-06-25 | — | — | EP | disclosed |