Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 10/20 | 0.44 |
| ▸ | GAA | P10253 | 10/20 | 0.44 |
| ▸ | SI | P14410 | 10/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 10/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6696707 | 0.99 | MGAM (0.43) | MGAMGAASIMGAM2PLA2G2A | |
| SCHEMBL6162618 | 0.91 | MGAM (0.45) | MGAMGAASIMGAM2 | |
| SCHEMBL6165742 | 0.90 | MGAM (0.44) | MGAMGAASIMGAM2 | |
| SCHEMBL6166093 | 0.88 | MGAM (0.47) | MGAMGAASIMGAM2 | |
| SCHEMBL6164752 | 0.87 | GAA (0.46) | MGAMGAASIMGAM2 | |
| SCHEMBL6163716 | 0.86 | MGAM (0.40) | MGAMGAASIMGAM2 | |
| SCHEMBL6162111 | 0.85 | ALDH1A1 (0.48) | MGAMGAASIMGAM2 | |
| SCHEMBL6165614 | 0.84 | ITGB3 (0.49) | MGAMGAASIMGAM2 | |
| SCHEMBL6165316 | 0.83 | MGAM (0.41) | MGAMGAASIMGAM2 | |
| SCHEMBL6162205 | 0.83 | ITGB3 (0.46) | MGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254133-A2 | INDOL-3-YL DERIVATIVES | MERCK PATENT GmbH (DE) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001058893-A2 | INDOL-3-YL DERIVATIVES AND THEIR USE AS INTEGRIN INHIBITORS | MERCK PATENT GMBH (DE) | 2001-08-16 | — | — | WO | disclosed |