Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | PREP | P48147 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364916 | 1.00 | SPHK1 (0.32) | SPHK1EPHX1CHRM2CHRM1PREP | |
| SCHEMBL7280493 | 0.75 | EPHX1 (0.33) | SPHK1EPHX1HPGDKDM4E | |
| SCHEMBL7284224 | 0.75 | EPHX1 (0.33) | SPHK1EPHX1HPGDKDM4E | |
| SCHEMBL9183699 | 0.75 | EPHX1 (0.33) | SPHK1EPHX1HPGDKDM4E | |
| SCHEMBL10378982 | 0.72 | SPHK1 (0.33) | SPHK1 | |
| SCHEMBL8551293 | 0.71 | SPHK1 (0.34) | SPHK1CHRM2CHRM1CHRM3 | |
| SCHEMBL7284303 | 0.71 | SPHK1 (0.34) | SPHK1 | |
| SCHEMBL8554509 | 0.70 | SPHK1 (0.36) | SPHK1CHRM2CHRM1PREPCHRM3 | |
| SCHEMBL25251925 | 0.70 | SPHK1 (0.34) | SPHK1CHRM2CHRM1CHRM3 | |
| SCHEMBL12534240 | 0.70 | SPHK1 (0.34) | SPHK1CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0578745-A1 | PHOSPHORUS CONTAINING COMPOUNDS AS INHIBITORS OF RETROVIRUSES | THE UPJOHN COMPANY (US) | 1994-01-19 | — | — | EP | disclosed |
| WO-1992017490-A1 | PHOSPHORUS CONTAINING COMPOUNDS AS INHIBITORS OF RETROVIRUSES | THE UPJOHN COMPANY (US) | 1992-10-15 | — | — | WO | disclosed |