Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554509 | 0.86 | SPHK1 (0.36) | SPHK1NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL9842234 | 0.81 | SPHK1 (0.35) | SPHK1CHRM2CHRM1CHRM3USP2 | |
| SCHEMBL8832441 | 0.79 | LMNA (0.36) | SMN1; SMN2 | |
| SCHEMBL14750633 | 0.75 | SPHK1 (0.38) | SPHK1NR1H2USP2SMN1; SMN2HCRTR2 | |
| SCHEMBL5495814 | 0.74 | SPHK1 (0.35) | SPHK1HCRTR2 | |
| SCHEMBL8112149 | 0.74 | SPHK1 (0.35) | SPHK1HCRTR2 | |
| SCHEMBL8145278 | 0.74 | SPHK1 (0.35) | SPHK1HCRTR2 | |
| SCHEMBL8112146 | 0.74 | SPHK1 (0.35) | SPHK1HCRTR2 | |
| SCHEMBL17356198 | 0.73 | SPHK1 (0.35) | SPHK1CHRM2CHRM1CHRM3USP2 | |
| SCHEMBL15936851 | 0.73 | SPHK1 (0.35) | SPHK1CHRM2CHRM1CHRM3USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712854-B1 | Baccatin derivatives and processes for preparing the same | TANABE SEIYAKU CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5608073-A | TAXANE INTERMEDIATES | TANABE SEIYAKU CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| US-5589502-A | ANTITUMOR | TANABE SEIYAKU CO., LTD. (JP) | 1996-12-31 | — | — | US | disclosed |
| US-5538995-A | Difluoroprostacyclins | ASAHI GLASS COMPANY LTD. (JP) | 1996-07-23 | — | — | US | disclosed |
| EP-0712854-A1 | Baccatin derivatives and processes for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1996-05-22 | — | — | EP | disclosed |