Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7365039 | 1.00 | MAOB (0.44) | MAOBMAOACYP1A2CYP2C9CYP1A1 | |
| SCHEMBL7338203 | 0.88 | HSD17B3 (0.42) | MAOBMAOACYP1A2CYP2C9CYP1A1 | |
| SCHEMBL7338205 | 0.88 | HSD17B3 (0.42) | MAOBMAOACYP1A2CYP2C9CYP1A1 | |
| SCHEMBL7329830 | 0.88 | NPC1 (0.44) | MAOBMAOACYP1A2CYP1A1CYP1B1 | |
| SCHEMBL7329824 | 0.88 | NPC1 (0.44) | MAOBMAOACYP1A2CYP1A1CYP1B1 | |
| SCHEMBL7339064 | 0.84 | HCAR2 (0.47) | MAOBMAOACYP1A2CYP1A1CYP1B1 | |
| SCHEMBL7330544 | 0.81 | KDM4E (0.44) | DCTPP1LMNAALDH1A1NPC1RAB9A | |
| SCHEMBL7330541 | 0.81 | KDM4E (0.44) | DCTPP1LMNAALDH1A1NPC1RAB9A | |
| SCHEMBL7336228 | 0.81 | LMNA (0.52) | MAOBMAOACYP1A1CYP1B1DCTPP1 | |
| SCHEMBL7336232 | 0.81 | LMNA (0.52) | MAOBMAOACYP1A1CYP1B1DCTPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191124-B1 | VIRICIDES | PHARMACIA & UPJOHN COMPANY | 2001-02-20 | — | — | US | disclosed |
| EP-0757692-A1 | METHANOL DERIVATIVES FOR TREATMENT OF RETROVIRAL INFECTIONS ESPECIALLY HIV INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029922-A1 | METHANOL DERIVATIVES FOR TREATMENT OF RETROVIRAL INFECTIONS ESPECIALLY HIV INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1995-11-09 | — | — | WO | disclosed |