Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.34 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.34 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359424 | 0.86 | ERCC1 (0.35) | ERCC1ERCC4ASAH1 | |
| SCHEMBL6803756 | 0.82 | ERCC1 (0.35) | ERCC1ERCC4ASAH1 | |
| SCHEMBL6803750 | 0.82 | ERCC1 (0.33) | ERCC1ERCC4ASAH1 | |
| SCHEMBL6800978 | 0.81 | ASAH1 (0.36) | ERCC1ERCC4ASAH1 | |
| SCHEMBL6800971 | 0.80 | ERCC1 (0.34) | ERCC1ERCC4ASAH1 | |
| SCHEMBL6807167 | 0.66 | ERCC1 (0.34) | ERCC1ERCC4ASAH1 | |
| SCHEMBL7366743 | 0.64 | LMNA (0.41) | — | |
| SCHEMBL6802745 | 0.64 | AXL (0.32) | — | |
| Oxalic Acid SCHEMBL10418863 | 0.54 | HSD11B1 (0.42) | — | |
| SCHEMBL13722060 | 0.53 | EPHA2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1159273-A1 | COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CATHEPSIN S | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000051998-A1 | COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CATHEPSIN S | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2000-09-08 | — | — | WO | disclosed |