Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CDC25C | P30307 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7397257 | 0.79 | KMT2A (0.56) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL27943796 | 0.77 | MAPT (0.58) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL3043741 | 0.75 | ALDH1A1 (0.55) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL443353 | 0.75 | TDP1 (0.64) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL31375357 | 0.75 | TDP1 (0.64) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL29031938 | 0.74 | CYP1A2 (0.59) | MEN1KMT2ALMNAGAA | |
| SCHEMBL3250031 | 0.74 | TDP1 (0.62) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| Potassium SCHEMBL1531376 | 0.74 | TDP1 (0.62) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL237798 | 0.74 | TDP1 (0.62) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL3250030 | 0.74 | TDP1 (0.62) | MEN1KMT2AMAPTSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0538384-A4 | OXAMIDES | SMITHKLINE BEECHAM CORP (US) | 1995-04-12 | — | — | EP | disclosed |
| US-5393788-A | Phenylalkyl oxamides | SMITHKLINE BEECHAM CORPORATION (US) | 1995-02-28 | — | — | US | disclosed |
| EP-0538384-A1 | OXAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-04-28 | — | — | EP | disclosed |
| WO-1992000968-A1 | OXAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1992-01-23 | — | — | WO | disclosed |