Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29626483 | 0.93 | MEN1 (0.42) | EPHX2MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL20223702 | 0.87 | TSHR (0.45) | PAOXEPHX2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14725908 | 0.87 | ALDH1A1 (0.56) | PAOXEPHX2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL26981157 | 0.85 | ALDH1A1 (0.53) | EPHX2MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL16526271 | 0.85 | HDAC6 (0.40) | PAOXMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3316187 | 0.82 | TSHR (0.42) | PAOXMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL21664615 | 0.82 | ALDH1A1 (0.52) | EPHX2MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21341652 | 0.82 | ALDH1A1 (0.52) | EPHX2MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13566485 | 0.80 | TSHR (0.45) | PAOXEPHX2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22266509 | 0.80 | ALDH1A1 (0.48) | EPHX2MEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0578745-A1 | PHOSPHORUS CONTAINING COMPOUNDS AS INHIBITORS OF RETROVIRUSES | THE UPJOHN COMPANY (US) | 1994-01-19 | — | — | EP | disclosed |
| WO-1992017490-A1 | PHOSPHORUS CONTAINING COMPOUNDS AS INHIBITORS OF RETROVIRUSES | THE UPJOHN COMPANY (US) | 1992-10-15 | — | — | WO | disclosed |