Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26981157 | 0.98 | ALDH1A1 (0.53) | ALDH1A1ADRA1ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL31631006 | 0.92 | ALDH1A1 (0.55) | ALDH1A1ADRA1ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL31631394 | 0.91 | PRMT1 (0.50) | ALDH1A1ADRA1AMEN1KMT2APRMT1 | |
| SCHEMBL25408551 | 0.90 | PRMT1 (0.48) | ALDH1A1ADRA1AMEN1KMT2APRMT1 | |
| SCHEMBL30771466 | 0.90 | PRMT1 (0.48) | ALDH1A1ADRA1AMEN1KMT2APRMT1 | |
| SCHEMBL30018345 | 0.89 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MEN1KMT2AEPHX2 | |
| SCHEMBL20223702 | 0.87 | TSHR (0.45) | ALDH1A1SMN1; SMN2MEN1KMT2AEPHX2 | |
| SCHEMBL7365096 | 0.87 | PAOX (0.42) | ALDH1A1SMN1; SMN2MEN1KMT2AEPHX2 | |
| SCHEMBL23705000 | 0.87 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL17749225 | 0.87 | ADRA1A (0.44) | ALDH1A1ADRA1AMEN1KMT2APRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130053315-A1 | NOVEL GLP-1 DERIVATIVES | NOVO NORDISK A/S | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053315-A1 | NOVEL GLP-1 DERIVATIVES | GLP1R, GIPR, IAPP | ALDH1A1 3523/4885ADRA1A 809/4885SMN1; SMN2 3474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.