Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 4/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7916733 | 1.00 | TSHR (0.44) | TSHRMAPTMEN1KMT2ACES1 | |
| SCHEMBL7361151 | 0.77 | MAPT (0.47) | MAPTMEN1KMT2ACES1CA1 | |
| SCHEMBL1509529 | 0.73 | APP (0.60) | TSHRMAPTMEN1KMT2A | |
| SCHEMBL3099878 | 0.73 | APP (0.60) | TSHRMAPTMEN1KMT2A | |
| SCHEMBL11223878 | 0.72 | MAPT (0.40) | MAPTMEN1KMT2ALOXL2CA1 | |
| SCHEMBL11223881 | 0.72 | MAPT (0.40) | MAPTMEN1KMT2ALOXL2CA1 | |
| SCHEMBL17629196 | 0.72 | MAPT (0.50) | MAPTMEN1KMT2ACES1LOXL2 | |
| SCHEMBL5578350 | 0.72 | MAPT (0.50) | MAPTMEN1KMT2ACES1LOXL2 | |
| SCHEMBL28016398 | 0.71 | TSHR (0.56) | TSHRMEN1KMT2ACES1IDO1 | |
| SCHEMBL7928526 | 0.71 | IDO1 (0.37) | MAPTMEN1KMT2AIDO1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000044712-A1 | N-HYDROXYFORMAMIDE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 2000-08-03 | — | — | WO | disclosed |