Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361151 | 0.84 | MAPT (0.47) | MAPTHSD17B10MEN1KMT2AACHE | |
| SCHEMBL17629196 | 0.79 | MAPT (0.50) | MAPTHSD17B10MEN1KMT2AACHE | |
| SCHEMBL514483 | 0.76 | HSD17B10 (0.56) | MAPTHSD17B10MEN1KMT2AACHE | |
| SCHEMBL223594 | 0.75 | MEN1 (0.59) | MAPTHSD17B10MEN1KMT2AACHE | |
| SCHEMBL3328543 | 0.75 | MAPT (0.79) | MAPTHSD17B10MEN1KMT2AACHE | |
| SCHEMBL4163474 | 0.75 | MAPT (0.79) | MAPTHSD17B10MEN1KMT2AACHE | |
| SCHEMBL22567 | 0.74 | ALDH1A1 (0.72) | HSD17B10MEN1KMT2AACHEALDH1A1 | |
| SCHEMBL27909482 | 0.74 | ALDH1A1 (0.72) | HSD17B10MEN1KMT2AACHEALDH1A1 | |
| SCHEMBL8934649 | 0.73 | MAPT (0.76) | MAPTHSD17B10MEN1KMT2AACHE | |
| SCHEMBL8934655 | 0.73 | MAPT (0.76) | MAPTHSD17B10MEN1KMT2AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3838890-B1 | METHOD FOR PREPARING 18F-BPA AND INTERMEDIATE | NEUBORON MEDTECH LTD (CN) | 2023-10-04 | — | — | EP | claimed |
| US-20230242555-A1 | METHOD FOR PREPARING 18F-BPA AND INTERMEDIATE | NEUBORON MEDTECH LTD. (CN) | 2023-08-03 | — | — | US | claimed |
| CN-110835310-B | Intermediate, preparation method and application | 南京中硼联康医疗科技有限公司 | 2022-09-20 | — | — | CN | claimed |
| CN-110835352-B | Preparation method18Process for F-BPA | 南京中硼联康医疗科技有限公司 | 2022-05-24 | — | — | CN | claimed |
| EP-0648220-A1 | DEUTERATED NUCLEOSIDES | CHATTOPADHYAYA, Jyoti (SE) | 1995-04-19 | — | — | EP | claimed |
| WO-1993025566-A1 | DEUTERATED NUCLEOSIDES | CHATTOPADHYAYA JYOTI (SE) | 1993-12-23 | — | — | WO | claimed |
| EP-3838890-B1 | METHOD FOR PREPARING 18F-BPA AND INTERMEDIATE | NEUBORON MEDTECH LTD (CN) | 2023-10-04 | — | — | EP | disclosed |
| US-20230242555-A1 | METHOD FOR PREPARING 18F-BPA AND INTERMEDIATE | NEUBORON MEDTECH LTD. (CN) | 2023-08-03 | — | — | US | disclosed |
| US-11655261-B2 | Method for preparing 18F-BPA and intermediate | NEUBORON MEDTECH LTD. (CN) | 2023-05-23 | — | — | US | disclosed |
| CN-110835310-B | Intermediate, preparation method and application | 南京中硼联康医疗科技有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-110835352-B | Preparation method18Process for F-BPA | 南京中硼联康医疗科技有限公司 | 2022-05-24 | — | — | CN | disclosed |
| CN-113773337-A | Radiolabeled boron-containing compounds, methods of preparation and uses | 南京中硼联康医疗科技有限公司 | 2021-12-10 | — | — | CN | disclosed |
| US-20210230192-A1 | METHOD FOR PREPARING 18F-BPA AND INTERMEDIATE | NEUBORON MEDTECH LTD. (CN) | 2021-07-29 | — | — | US | disclosed |
| EP-3838890-A1 | METHOD FOR PREPARING 18F-BPA AND INTERMEDIATE | Neuboron Medtech Ltd. (CN) | 2021-06-23 | — | — | EP | disclosed |
| CN-110835352-A | Preparation method18Process for F-BPA | 南京中硼联康医疗科技有限公司 | 2020-02-25 | — | — | CN | disclosed |
| CN-110835310-A | Intermediate, preparation method and application | 南京中硼联康医疗科技有限公司 | 2020-02-25 | — | — | CN | disclosed |
| WO-2020035011-A1 | METHOD FOR PREPARING 18F-BPA AND INTERMEDIATE | 南京中硼联康医疗科技有限公司 | 2020-02-20 | — | — | WO | disclosed |
| US-20070244055-A1 | Conjugates useful in the treatment of prostate cancer | BRADY STEPHEN F | 2007-10-18 | — | — | US | disclosed |
| US-20070129309-A1 | Conjugates useful in the treatment of prostate cancer | BRADY STEPHEN F | 2007-06-07 | — | — | US | disclosed |
| US-20050119166-A1 | Conjugates useful in the treatment of prostate cancer | BRADY STEPHEN F (US) | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242555-A1 | METHOD FOR PREPARING 18F-BPA AND INTERMEDIATE | CYP19A1, SHBG, ESR1 | MAPT 1915/4885HSD17B10 258/4885MEN1 691/4885 |
| US-20050119166-A1 | Conjugates useful in the treatment of prostate cancer | BPHL, KLK3, DNPEP | MAPT 1745/4885HSD17B10 365/4885MEN1 3756/4885 |
| US-20070129309-A1 | Conjugates useful in the treatment of prostate cancer | BPHL, KLK3, DNPEP | MAPT 1858/4885HSD17B10 275/4885MEN1 3441/4885 |
| US-20070244055-A1 | Conjugates useful in the treatment of prostate cancer | BPHL, KLK3, DNPEP | MAPT 1745/4885HSD17B10 365/4885MEN1 3756/4885 |
| US-20210230192-A1 | METHOD FOR PREPARING 18F-BPA AND INTERMEDIATE | CYP19A1, SHBG, ESR1 | MAPT 1915/4885HSD17B10 258/4885MEN1 691/4885 |
| US-11655261-B2 | Method for preparing 18F-BPA and intermediate | CYP19A1, SHBG, ESR1 | MAPT 1915/4885HSD17B10 258/4885MEN1 691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.