Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 15/20 | 0.48 |
| ▸ | DRD2 | P14416 | 11/20 | 0.48 |
| ▸ | HTR7 | P34969 | 9/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.46 |
| ▸ | HTR1A | P08908 | 4/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367061 | 0.88 | DRD2 (0.47) | HTR2ADRD2HTR7KCNH2HTR1A | |
| SCHEMBL7367433 | 0.84 | DRD2 (0.55) | HTR2ADRD2HTR7KCNH2SLC6A4 | |
| SCHEMBL8113107 | 0.75 | HTR2A (0.60) | HTR2ADRD2HTR7KCNH2HTR1A | |
| SCHEMBL13448255 | 0.74 | HTR2A (0.60) | HTR2ADRD2HTR7KCNH2HTR1A | |
| SCHEMBL8113389 | 0.72 | HTR2A (0.57) | HTR2ADRD2HTR7KCNH2HTR1A | |
| SCHEMBL7368733 | 0.72 | DRD2 (0.53) | HTR2ADRD2HTR7KCNH2HTR1A | |
| SCHEMBL22302778 | 0.70 | DRD2 (0.63) | HTR2ADRD2HTR7KCNH2HTR1A | |
| SCHEMBL7365706 | 0.70 | DRD2 (0.55) | HTR2ADRD2HTR7KCNH2SLC6A4 | |
| SCHEMBL7365317 | 0.69 | HTR2A (0.49) | HTR2ADRD2HTR7KCNH2HTR1A | |
| SCHEMBL7360772 | 0.69 | DRD2 (0.53) | HTR2ADRD2HTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780474-A | ADMINISTERING IN THE TREATMENT OF PSYCHOTIC DISORDERS, ANXIO-DEPRESSIVE DISORDERS AND AGGRESSIVENESS | ADIR ET COMPAGNIE (FR) | 1998-07-14 | — | — | US | claimed |
| US-5780474-A | ADMINISTERING IN THE TREATMENT OF PSYCHOTIC DISORDERS, ANXIO-DEPRESSIVE DISORDERS AND AGGRESSIVENESS | ADIR ET COMPAGNIE (FR) | 1998-07-14 | — | — | US | disclosed |