Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 5/20 | 0.42 |
| ▸ | CES1 | P23141 | 4/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1193777 | 0.79 | L3MBTL1 (0.64) | L3MBTL1EPHX2NPSR1HSD11B1HSD17B10 | |
| SCHEMBL25359614 | 0.76 | L3MBTL1 (0.64) | L3MBTL1EPHX2NPSR1HSD11B1HSD17B10 | |
| SCHEMBL1193302 | 0.73 | L3MBTL1 (0.60) | L3MBTL1EPHX2NPSR1HSD11B1HSD17B10 | |
| SCHEMBL12344537 | 0.72 | L3MBTL1 (1.00) | L3MBTL1EPHX2NPSR1HSD11B1HSD17B10 | |
| SCHEMBL25358145 | 0.72 | L3MBTL1 (0.68) | L3MBTL1EPHX2NPSR1HSD11B1HSD17B10 | |
| SCHEMBL9744305 | 0.72 | L3MBTL1 (0.68) | L3MBTL1EPHX2NPSR1HSD11B1HSD17B10 | |
| SCHEMBL9743896 | 0.72 | L3MBTL1 (0.73) | L3MBTL1EPHX2NPSR1HSD11B1HSD17B10 | |
| SCHEMBL27451035 | 0.71 | L3MBTL1 (0.61) | L3MBTL1EPHX2NPSR1FAAH | |
| SCHEMBL14503294 | 0.71 | L3MBTL1 (0.52) | L3MBTL1EPHX2HSD11B1KMT2AHSD17B10 | |
| SCHEMBL15224188 | 0.70 | L3MBTL1 (0.66) | L3MBTL1EPHX2NPSR1HSD11B1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020103192-A1 | Inhibitors of histone deacetylase | ABBOTT LABORATORIES | 2002-08-01 | — | — | US | claimed |
| US-20020177594-A1 | Inhibitors of histone deacetylase | ABBOTT LABORATORIES | 2002-11-28 | — | — | US | disclosed |
| US-20020103192-A1 | Inhibitors of histone deacetylase | ABBOTT LABORATORIES | 2002-08-01 | — | — | US | disclosed |
| WO-2002046129-A2 | INHIBITORS OF HISTONE DEACETYLASE | ABBOTT LABORATORIES (US) | 2002-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020103192-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC5, HDAC4 | L3MBTL1 2415/4885EPHX2 3092/4885NPSR1 4353/4885 |
| US-20020177594-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC11, HDAC3 | L3MBTL1 2041/4885EPHX2 3982/4885NPSR1 4129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.