Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14618042 | 0.82 | EPHX1 (0.36) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL208786 | 0.79 | TDP1 (0.52) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL21375006 | 0.78 | TDP1 (0.41) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL21375013 | 0.76 | ACHE (0.52) | TDP1MEN1GAAKMT2A | |
| SCHEMBL13686206 | 0.74 | TDP1 (0.33) | TDP1 | |
| Phosphonic Acid SCHEMBL8156611 | 0.73 | TDP1 (0.37) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL14586293 | 0.72 | PTGER1 (0.32) | — | |
| SCHEMBL23992120 | 0.72 | — | — | |
| SCHEMBL9637794 | 0.72 | GAA (0.35) | GAA | |
| SCHEMBL9637796 | 0.71 | LDHA (0.33) | MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0021620-A1 | Water-soluble peptides affecting gonadal function | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1981-01-07 | — | — | EP | claimed |
| US-4018726-A | [D-Phe6 ]-LH-RH and intermediates therefor | SCHALLY ANDREW VICTOR | 1977-04-19 | — | — | US | claimed |
| US-4010125-A | [D-Trp6 ]-LH-RH and intermediates therefor | SCHALLY ANDREW VICTOR | 1977-03-01 | — | — | US | claimed |
| EP-0624163-A1 | CYCLIC CALCITONIN DERIVATIVES AND METHOD FOR THEIR PRODUCTION | Smithkline Beecham Farmaceutici S.p.A. (IT) | 1994-11-17 | — | — | EP | disclosed |
| WO-1993015106-A1 | CYCLIC CALCITONINE DERIVATIVES AND METHOD FOR THEIR PRODUCTION | SMITHKLINE BEECHAM FARMACEUTICI S.P.A. (IT) | 1993-08-05 | — | — | WO | disclosed |
| EP-0098457-B1 | (1S,2R,3R)- AND (1R,2S,3S)-NITRILO-1-CARBONYL-3-METHYL-2-OXY-HEPTANES AND -HEPT-5-ENES USEFUL IN THE TOTAL SYNTHESIS OF CYCLOSPORINS AND PROCESSES FOR THEIR PRODUCTION | SANDOZ AG (CH) | 1987-08-05 | — | — | EP | disclosed |
| EP-0181121-A2 | Novel polypeptide and process for producing the same | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1986-05-14 | — | — | EP | disclosed |
| US-4554351-A | STEREOISOMERS | SANDOZ LTD. (CH) | 1985-11-19 | — | — | US | disclosed |
| EP-0098457-A2 | (1S,2R,3R)- and (1R,2S,3S)-nitrilo-1-carbonyl-3-methyl-2-oxy-heptanes and -hept-5-enes useful in the total synthesis of cyclosporins and processes for their production | SANDOZ AG (CH) | 1984-01-18 | — | — | EP | disclosed |
| EP-0098456-A2 | Peptides comprising a (1S,2R,3R)- or (1R,2S,3S)-1-nitrilo-1-carbonyl-3-methyl-2-oxy-heptane or -hept-5-ene residue useful in the total synthesis of cyclosporins, and processes for their production | SANDOZ AG (CH) | 1984-01-18 | — | — | EP | disclosed |
| US-4396542-A | Method for the total synthesis of cyclosporins, novel cyclosporins and novel intermediates and methods for their production | SANDOZ LTD. (CH) | 1983-08-02 | — | — | US | disclosed |
| EP-0047079-A1 | Nonapeptides affecting gonadal function | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1982-03-10 | — | — | EP | disclosed |
| EP-0034567-A2 | A method for the total synthesis of cyclosporins and novel cyclosporins | SANDOZ AG (CH) | 1981-08-26 | — | — | EP | disclosed |
| EP-0021620-A1 | Water-soluble peptides affecting gonadal function | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1981-01-07 | — | — | EP | disclosed |
| US-4018726-A | [D-Phe6 ]-LH-RH and intermediates therefor | SCHALLY ANDREW VICTOR | 1977-04-19 | — | — | US | disclosed |