Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363627 | 1.00 | HCRTR2 (0.32) | HCRTR2EPHX1ALDH1A1MMP3ADAM17 | |
| SCHEMBL7363622 | 1.00 | HCRTR2 (0.32) | HCRTR2EPHX1ALDH1A1MMP3ADAM17 | |
| SCHEMBL7365730 | 0.85 | RABGGTB (0.33) | HCRTR2EPHX1 | |
| SCHEMBL7365732 | 0.85 | RABGGTB (0.33) | HCRTR2EPHX1 | |
| SCHEMBL9556791 | 0.82 | SPHK1 (0.34) | HCRTR2EPHX1 | |
| SCHEMBL10528950 | 0.81 | SPHK1 (0.35) | HCRTR2EPHX1ALDH1A1 | |
| SCHEMBL10596441 | 0.80 | MMP3 (0.32) | MMP3ADAM17 | |
| SCHEMBL10596454 | 0.80 | MMP3 (0.32) | MMP3ADAM17 | |
| SCHEMBL10596447 | 0.80 | MMP3 (0.32) | MMP3ADAM17 | |
| SCHEMBL9556455 | 0.79 | SPHK1 (0.34) | HCRTR2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415981-A4 | RETROVIRAL PROTEASE INHIBITORS | — | 1991-10-09 | — | — | EP | disclosed |
| EP-0415981-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |
| WO-1989010752-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |