Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.63 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.63 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7364790 | 0.82 | IMPDH2 (0.77) | IMPDH2IMPDH1ESR1GABRPGABRD | |
| Methyl Alcohol SCHEMBL27844152 | 0.81 | IMPDH2 (0.89) | IMPDH2IMPDH1ESR1GABRPGABRD | |
| SCHEMBL5015694 | 0.80 | IMPDH2 (0.75) | IMPDH2IMPDH1ESR1GABRPGABRD | |
| SCHEMBL91366 | 0.80 | IMPDH2 (1.00) | IMPDH2IMPDH1ESR1GABRPGABRD | |
| SCHEMBL30389000 | 0.80 | IMPDH2 (1.00) | IMPDH2IMPDH1ESR1GABRPGABRD | |
| Maleic Acid SCHEMBL28775310 | 0.79 | IMPDH2 (0.73) | IMPDH2IMPDH1ESR1GABRPGABRD | |
| Fumaric Acid SCHEMBL28775322 | 0.79 | IMPDH2 (0.73) | IMPDH2IMPDH1ESR1GABRPGABRD | |
| Hydrochloric Acid SCHEMBL27803164 | 0.78 | IMPDH2 (0.96) | IMPDH2IMPDH1ESR1GABRPGABRD | |
| SCHEMBL28194905 | 0.78 | IMPDH2 (0.96) | IMPDH2IMPDH1ESR1GABRPGABRD | |
| Ethoxycarbonyl Group SCHEMBL27718926 | 0.77 | IMPDH2 (0.65) | IMPDH2IMPDH1ESR1GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043257-A | ANTICOAGULANT; PYRIDINE SUBSTITUTED INDAZOLE COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-03-28 | — | — | US | disclosed |
| EP-0960102-A1 | AMIDINOINDOLES, AMIDINOAZOLES, AND ANALOGS THEREOF AS INHIBITORS OF FACTOR Xa AND OF THROMBIN | Du Pont Pharmaceuticals Company (US) | 1999-12-01 | — | — | EP | disclosed |
| US-5886191-A | ANTICOAGULANTS | DUPONT PHARMACEUTICALS COMPANY (US) | 1999-03-23 | — | — | US | disclosed |
| WO-1998001428-A1 | AMIDINOINDOLES, AMIDINOAZOLES, AND ANALOGS THEREOF AS INHIBITORS OF FACTOR Xa AND OF THROMBIN | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-01-15 | — | — | WO | disclosed |